Uncovering the Protective Neurologic Mechanisms of Hypofractionated FLASH Radiotherapy.
Yasaman AlaghbandBarrett D AllenEniko A KramárRichard ZhangOlivia G G DraysonNing RuBenoit PetitAymeric AlmeidaNgoc-Lien DoanMarcelo A WoodJanet E BaulchPaola Ballesteros-ZebadúaMarie-Catherine VozeninCharles L LimoliPublished in: Cancer research communications (2023)
Functional preservation of cognition and LTP after hypofractionated FLASH-RT are linked to a protection of synaptic integrity and a reduction in neuroinflammation over protracted after irradiation times.
Keyphrases
- radiation therapy
- radiation induced
- locally advanced
- early stage
- brain metastases
- traumatic brain injury
- lipopolysaccharide induced
- mild cognitive impairment
- lps induced
- cognitive impairment
- white matter
- cerebral ischemia
- prefrontal cortex
- small cell lung cancer
- squamous cell carcinoma
- multiple sclerosis
- rectal cancer
- inflammatory response
- brain injury
- subarachnoid hemorrhage