Genetic differences between type 1 diabetes with and without other autoimmune diseases.

Kanako ShimuraJunnosuke MiuraManabu KawamotoYasushi KawaguchiHisashi YamanakaYasuko Uchigata

Published in: Diabetes/metabolism research and reviews (2018)

The -1123G > C SNP in the PTPN22 gene promoter and HLA DRB1*0405-DQB1*0401 might influence the concurrence of systemic and organ-specific ADs in patients with type 1 diabetes.

Keyphrases

genome wide
dna methylation
type diabetes
copy number
gene expression
glycemic control
transcription factor
cardiovascular disease
insulin resistance
drug induced