The Association Between Pre-Booster Vaccination Antibody Levels and the Risk of SARS-CoV-2 Infection.
Noam BardaMichal CanettiMayan GilboaKeren AsrafVictoria IndenboimYael Weiss-OttolenghiSharon AmitDaniel ZubliRam DoolmanElla MendelsonLaurence S FreedmanYitshak KreissYaniv LustigGili Regev-YochayPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
The correlation between Anti-SARS-CoV-2 antibody levels and infection was reported. Here, we estimated the role of pre-fourth-dose levels using data from 1,098 health-care-workers. The risk of infection was reduced by 46% (95% CI: 29-59%) with a 10-fold increase in pre-booster levels. Pre-booster antibody levels could be used to optimally time boosters.