Local euchromatin enrichment in lamina-associated domains anticipates their repositioning in the adipogenic lineage.

Julia Madsen-ØsterbyeMohamed AbdelhalimMarie-Odile BaudementPhilippe Collas

Published in: Genome biology (2022)

We conclude that LADs are predictable structural features of adipose nuclear architecture that restrain non-adipogenic genes in a repressive environment.

Keyphrases

genome wide
adipose tissue
insulin resistance
single cell
bioinformatics analysis
genome wide identification
type diabetes
dna methylation
gene expression
genome wide analysis