Association between diesel exhaust exposure and mitochondrial DNA methylation.

Wei Jie SeowWei HuYufei DaiRoel C H VermeulenHyang-Min ByunJason Y Y WongBryan A BassigBatel BlechterHuawei DuanYong NiuGeorge DownwardShuguang LengBu-Tian JiWei FuJun XuKees MeliefsteJufang YangDianzhi RenMeng YeTao MengPing BinH Dean HosgoodDebra T SilvermanNathaniel RothmanYuxin ZhengQing Lan

Published in: Carcinogenesis (2022)

Our findings suggest that DEE exposure perturbs mtDNA methylation, which may be of importance for tumorigenesis.

Keyphrases

dna methylation
genome wide
copy number
gene expression
oxidative stress
mitochondrial dna
particulate matter
air pollution