SARS-CoV-2 host cell entry: an in silico investigation of potential inhibitory roles of terpenoids.

Gideon Ampoma GyebiOludare M OgunyemiIbrahim M IbrahimOlalekan B OgunroAdegbenro P AdegunloyeSaheed O Afolabi

Published in: Journal, genetic engineering & biotechnology (2021)

The identified terpenoids from this study provides core structure that can be exploited for further lead optimization to design drugs against SARS-CoV-2 cell-mediated entry proteins. They are therefore recommended for further in vitro and in vivo studies towards developing entry inhibitors against the ongoing COVID-19 pandemic.

Keyphrases

sars cov
single cell
cell therapy
respiratory syndrome coronavirus
stem cells
molecular docking
risk assessment
mesenchymal stem cells
coronavirus disease
climate change