STK4 deficiency and epidermodysplasia verruciformis-like lesions: A case report.
Paula A Gutierrez-MarinLina Maria Castano-JaramilloNatalia Velez-TiradoMilena Villamil-OsorioEsteban PatiñoMaria Fernanda ReinaMaribel Trujillo HernandezPublished in: Pediatric dermatology (2023)
Serine/threonine kinase 4 deficiency (STK4 or MST1, OMIM:614868) is an autosomal recessive (AR) combined immunodeficiency that can present with skin lesions such as epidermodysplasia verruciformis-like lesions (EVLL). Herein, we describe a 17-year-old male patient born from consanguineous parents presenting with recurrent respiratory infections, verruciform plaques, poikiloderma, chronic benign lymphoproliferation, and Sjögren syndrome with suspected interstitial lymphocytic pneumonia.