Concordance of Immunohistochemistry-Based and Gene Expression-Based Subtyping in Breast Cancer.
Johanna HolmNancy Yiu-Lin YuAnnelie JohanssonAlexander PlonerPer HallLinda Sofie LindströmKamila CzenePublished in: JNCI cancer spectrum (2020)
All surrogate classifiers had limited ability to distinguish between PAM50 luminal A and B, but patterns of misclassifications differed. PAM50 subtyping appeared to yield larger separation of survival between luminal subtypes than any of the surrogate classifications.