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Concordance of Immunohistochemistry-Based and Gene Expression-Based Subtyping in Breast Cancer.

Johanna HolmNancy Yiu-Lin YuAnnelie JohanssonAlexander PlonerPer HallLinda Sofie LindströmKamila Czene
Published in: JNCI cancer spectrum (2020)
All surrogate classifiers had limited ability to distinguish between PAM50 luminal A and B, but patterns of misclassifications differed. PAM50 subtyping appeared to yield larger separation of survival between luminal subtypes than any of the surrogate classifications.
Keyphrases
  • gene expression
  • dna methylation
  • free survival
  • young adults