Proinflammatory phenotype of B10 and B10pro cells elicited by TNF-α in rheumatoid arthritis.
Fanlei HuLianjie ShiXiaohang LiuYingjia ChenXia ZhangYuan JiaXu LiuJianping GuoHuaqun ZhuHongjiang LiuLiling XuYingni LiPing WangXiangyu FangJimeng XueYang XieChaonan WeiJing SongXi ZhengYan-Ying LiuYuhui LiLimin RenDakang XuLiwei LuXiaoyan QiuRong MuJing HeMin WangXuan ZhangWanli LiuZhanguo LiPublished in: Annals of the rheumatic diseases (2024)
TNF-α provoked the proinflammatory phenotype of B10 and B10pro cells by disturbing SHIP-1 in RA, contributing to the disease development. Reinstating the immunosuppressive property of B10 and B10pro cells might represent novel therapeutic approaches for RA.