Spleen enlargement assessment using computed tomography: which coefficient correlates the strongest with the real volume of the spleen?

Coefficient calculated from maximal length, vertical height and hilum thickness correlates the strongest with spleen volume and can be utilized for monitoring of spleen volume instead of obsolete splenic index. The most suitable for quick splenomegaly screening is two-dimensional coefficient (maximal length × vertical height), with the cut-off 115 cm2.