Effect of Levothyroxine Supplementation on the Cardiac Morphology and Function in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis.
Xichang WangHaoyu WangQiuxian LiPing WangYumin XingFan ZhangJiashu LiZhongyan ShanPublished in: The Journal of clinical endocrinology and metabolism (2022)
Judging from the obvious changes in the CO, LVEF, and E/A ratio, LT4 supplementation can effectively improve the cardiac systolic and diastolic dysfunction prevalent in SCH patients. This study provides evidence of the recommendation for LT4 supplementation in adult SCH patients.