Association of obesity with postacute sequelae of COVID-19.
Ali AminianJames BenaKevin M PantaloneBartolome BurgueraPublished in: Diabetes, obesity & metabolism (2021)
Obesity is a major risk factor for the development of severe coronavirus disease 2019 (COVID-19) infection and mortality. However, it is not known whether patients with obesity are at a greater risk of developing postacute sequelae of COVID-19 (PASC). In a median follow-up time of 8 months and counting from 30 days following a positive viral test of 2839 patients who did not require intensive care unit admission and survived the acute phase of COVID-19, 1230 (43%) patients required medical diagnostic tests, 1255 (44%) patients underwent hospital admission, and 29 (1%) patients died. Compared with patients with a normal body mass index (BMI), the risk of hospital admission was 28% and 30% higher in patients with moderate and severe obesity, respectively. The need for diagnostic tests to assess different medical problems, compared with patients with normal BMI, was 25% and 39% higher in patients with moderate and severe obesity, respectively. The findings of this study suggest that moderate and severe obesity (BMI ≥ 35 kg/m2 ) are associated with a greater risk of PASC.
Keyphrases
- weight gain
- body mass index
- coronavirus disease
- insulin resistance
- metabolic syndrome
- weight loss
- high fat diet induced
- type diabetes
- sars cov
- end stage renal disease
- intensive care unit
- emergency department
- healthcare
- early onset
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- ejection fraction
- prognostic factors
- high intensity
- mental health
- cardiovascular disease
- physical activity
- skeletal muscle
- coronary artery disease
- mechanical ventilation
- adverse drug