Bone marrow sFRP5 level is negatively associated with bone formation markers.

Hong ChenY HeD WuG DaiC ZhaoW HuangD Jiang

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2016)

Bone marrow sFRP5 level is closely correlated with BMD and bone formation markers. sFRP5 may be a potential negative regulator of bone mass by inhibiting bone formation. It may exert its effects on bone metabolism in a paracrine, rather than endocrine manner.

Keyphrases

bone marrow
bone mineral density
mesenchymal stem cells
soft tissue
bone loss
bone regeneration
transcription factor
postmenopausal women
risk assessment