Regulation of PGLYRP1 and TREM-1 during Progression and Resolution of Gingival Inflammation.
A SilbereisenA K HallakGustavo Giacomelli NascimentoT SorsaGeorgios N BelibasakisR LopezNagihan BostanciPublished in: JDR clinical and translational research (2019)
The results of this study demonstrated the suitability of salivary TREM-1 and PGLYRP1 to reflect biofilm accumulation and removal and PGLYRP1 to monitor the progression and resolution of inflammation in gingivitis-susceptible individuals (fast responders). Combined with conventional risk factors, the molecular toolbox proposed here should be further validated in future studies to confirm whether it can be used for population-based monitoring and prevention of gingivitis.