Rapid Changes in Nasopharyngeal Antibiotic Resistance Gene Profiles After Short Courses of Antibiotics in a Pilot Study of Ambulatory Young Children.
Leigh M HowardKeerti L DantuluriNicole SoperIsaac P ThomsenCarlos G GrijalvaPublished in: Open forum infectious diseases (2021)
We quantified antibiotic resistance genes before and after short antibiotic courses in nasopharyngeal specimens from ambulatory children. Carriage of certain bacteria and resistance genes was common before antibiotics. After antibiotics, we observed substantial reductions in pneumococcal and Staphylococcus aureus carriage and rapid expansion in the abundance of certain resistance genes.
Keyphrases
- antibiotic resistance genes
- genome wide
- genome wide identification
- staphylococcus aureus
- wastewater treatment
- microbial community
- blood pressure
- genome wide analysis
- anaerobic digestion
- young adults
- bioinformatics analysis
- dna methylation
- copy number
- transcription factor
- escherichia coli
- fine needle aspiration
- ultrasound guided