Long-term mortality in heart failure with mid-range ejection fraction: systematic review and meta-analysis.

Deep Chandh RajaIndira SamarawickremaSouvik DasAbhinav MehtaLukah TuanSanjiv JainSanjay DixitFrank MarchlinskiWalter P AbhayaratnaPrashanthan SandersRajeev Kumar Pathak

Published in: ESC heart failure (2022)

The results of the study support that HFmrEF has better prognosis than HFrEF but similar prognosis when compared with HFpEF. Gender disparity between studies seems to influence the results between HFmrEF and HFrEF. Transition in left ventricular ejection fraction (LVEF), which could not be addressed in the study, may play a decisive role in determining outcomes. PROSPERO review registration number CRD42021277107.

Keyphrases

ejection fraction
aortic stenosis
heart failure
left ventricular
mental health
transcatheter aortic valve replacement
risk factors
cardiovascular disease
mitral valve
metabolic syndrome
adipose tissue
acute coronary syndrome
atrial fibrillation
insulin resistance
skeletal muscle
percutaneous coronary intervention