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Cabergoline Targets Multiple Pathways to Inhibit PRL Secretion and Increases Stromal Fibrosis.

Dongyun ZhangWilly HugoMarvin BergsneiderMarilene B WangWon KimKaram HanHarry V VintersAnthony P Heaney
Published in: European journal of endocrinology (2024)
Our scRNAseq studies revealed key differences in the transcriptomic features of CBG-treated and untreated PRLomas in both tumor and microenvironment cellular constituents, and for the first time describe previously unknown activation of CD8+ T cells following CBG-treatment which may play a role in the tumoricidal actions of CBG.
Keyphrases
  • single cell
  • stem cells
  • bone marrow
  • rna seq
  • case control
  • newly diagnosed
  • liver fibrosis