Cabergoline Targets Multiple Pathways to Inhibit PRL Secretion and Increases Stromal Fibrosis.
Dongyun ZhangWilly HugoMarvin BergsneiderMarilene B WangWon KimKaram HanHarry V VintersAnthony P HeaneyPublished in: European journal of endocrinology (2024)
Our scRNAseq studies revealed key differences in the transcriptomic features of CBG-treated and untreated PRLomas in both tumor and microenvironment cellular constituents, and for the first time describe previously unknown activation of CD8+ T cells following CBG-treatment which may play a role in the tumoricidal actions of CBG.