Evaluation of BRCA1 Gene Promoter Methylation Status in Sporadic Breast Cancer Patients in Southwest of Iran.

Hedieh HassaniAbdolhosein TalaeizadehMaryam Tahmasebi BirganiMahdi Bijanzadeh

Published in: Asian Pacific journal of cancer prevention : APJCP (2023)

Although 2 out of 74 patients resulted positive for methylation status, the healthy controls demonstrated no methylation. Consequently, there was inadequate evidence to confirm the association between BRCA1 gene promoter methylation in blood and the risk of developing breast cancer.

Keyphrases

genome wide
dna methylation
copy number
end stage renal disease
gene expression
newly diagnosed
chronic kidney disease
ejection fraction
prognostic factors
breast cancer risk
peritoneal dialysis
late onset
early onset