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Thyroid transcription factor 1 (TTF-1) negativity as a predictor of unfavorable response to EGFR-TKI therapy in advanced lung adenocarcinoma patients with EGFR mutations.

Xiaosheng DingWeiwei ShiBingxuan HanHanxiao ChenJia LiJuan AnLili ZhouWeiran XuHui ShiXixi ZhengYichun HuaXiao-Yan Li
Published in: Thoracic cancer (2023)
Patients with TTF-1-negative and EGFR-mutant LUAD show a diminished response to EGFR-TKIs.
Keyphrases
  • tyrosine kinase
  • small cell lung cancer
  • epidermal growth factor receptor
  • transcription factor
  • advanced non small cell lung cancer
  • dna binding