Hawthorn Leaf Flavonoids Protect against Diabetes-Induced Cardiomyopathy in Rats via PKC-α Signaling Pathway.

Qing Min Yuting Bai Yuchen Zhang Wei Yu Minli Zhang Dongyang Liu Tingting Diao Wei Lv

Published in: Evidence-based complementary and alternative medicine : eCAM (2017)

HLF has a protective effect against diabetic cardiomyopathy in rats. The mechanism may be involved in reducing oxidative stress and inflammation via inactivation of the PKC-α signaling pathway.

Keyphrases

signaling pathway
oxidative stress
diabetic rats
type diabetes
induced apoptosis
pi k akt
heart failure
epithelial mesenchymal transition
cardiovascular disease
high glucose
dna damage
ischemia reperfusion injury
glycemic control
protein kinase
endothelial cells
insulin resistance
endoplasmic reticulum stress