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A folic acid-enriched diet attenuates prostate involution in response to androgen deprivation.

Diya B JosephAnoop S ChandrashekarLi-Fang ChuJames A ThomsonChad M Vezina
Published in: The Prostate (2018)
Continuous exposure to a FA enriched diet slows prostate involution in response to androgen deprivation. Prostates from FA diet mice have increased secretory gene expression and increased luminal cell heights. The influence of dietary FA supplementation on the prostate response to androgen deprivation raises a future need to consider how dietary folic acid supplementation affects efficacy of androgen-reducing therapies for treating prostate disease.
Keyphrases
  • benign prostatic hyperplasia
  • prostate cancer
  • gene expression
  • weight loss
  • physical activity
  • dna methylation
  • single cell
  • type diabetes
  • cell therapy
  • bone marrow
  • adipose tissue
  • insulin resistance