Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis.
Christiane GraetzAdriane GrögerFelix LuessiAnke SalmenDaniela ZöllerJanine SchultzNelly SillerVinzenz FleischerBarbara BellenbergAchim BertheleViola BiberacherJoachim HavlaMichael HeckerReinhard HohlfeldCarmen Infante-DuarteJan Stefan KirschkeTania KümpfelRalf LinkerFriedemann PaulSteffen PfeufferPhilipp SämannGerrit ToengesFrank WeberUwe K ZettlAntje Jahn-EimermacherGisela AntonySergiu GroppaHeinz WiendlBernhard HemmerMark MühlauCarsten LukasRalf GoldChristina M LillFrauke ZippPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2018)
Smoking may have an unfavorable effect on the gray matter fraction as a potential measure of MS severity already in early MS. These findings may impact patients' counseling upon initial diagnosis of MS.
Keyphrases
- multiple sclerosis
- mass spectrometry
- body mass index
- white matter
- ms ms
- smoking cessation
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- physical activity
- cognitive decline
- peritoneal dialysis
- adipose tissue
- skeletal muscle
- resting state
- brain injury
- patient reported outcomes
- human health
- risk assessment
- human immunodeficiency virus
- blood brain barrier
- men who have sex with men