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Flow Cytometry Identifies a Spectrum of Maturation in Myeloid Neoplasms Having Plasmacytoid Dendritic Cell Differentiation.

Fatima HamadehAmad AwadallahHoward J MeyersonRose C Beck
Published in: Cytometry. Part B, Clinical cytometry (2019)
These cases demonstrate that high grade MNs, in particular AML, can exhibit PDC differentiation, with or without monocytic differentiation, in a manner distinct from MPDMN or BPDCN. The existence of MNs with immature PDC proliferations suggests that there is a broader spectrum of PDC-associated neoplasms than currently recognized. © 2019 International Clinical Cytometry Society.
Keyphrases
  • dendritic cells
  • flow cytometry
  • high grade
  • acute myeloid leukemia
  • immune response
  • single cell
  • genome wide
  • bone marrow