Versatility in the Brook Rearrangement for the Selective Ring-Opening of Three-Membered Rings.
Coralie TugnyFa-Guang ZhangIlan MarekPublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2018)
From a single α-silylated carbinol intermediate, easily accessible by carbometallation of cyclopropenes, various scaffolds featuring a quaternary carbon stereocenter could be obtained selectively. The selectivity towards these different products was achieved by either changing the experimental conditions or the nature of the organometallic species involved.
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