The role of the T-cell mediated immune response to Cytomegalovirus infection in intrauterine transmission.
María Soriano-RamosEstrella Esquivel-De la FuenteEliseo Albert VicentMaría de la CalleFernando Baquero-ArtigaoSara Domínguez-RodríguezMaría CabanesEnery Gómez-MontesAnna GoncéMarta Valdés-BangoMª Carmen Viñuela-BenéitezMaría Del Mar Muñoz-ChápuliJesús Saavedra-LozanoIrene Cuadrado PérezBegoña EncinasLaura Castells VilellaMaría de la Serna MartínezAlfredo TagarroPaula Rodríguez-MolinoEstela Giménez QuilesDiana García AlcázarAntonio García BurguilloMaría Dolores FolgueiraDavid NavarroDaniel Blázquez-Gameronull nullPublished in: PloS one (2023)
In this cohort of pregnant women with a primary CMV infection, no association was found between the presence of a CMV T-cell response at the time of maternal infection and the risk of intrauterine transmission. A detectable CMV viral load in the maternal blood at diagnosis of the primary maternal infection may represent a relevant biomarker associated with fetal transmission.