Ubiquitin-Conjugating Enzyme E2 L3 is Downregulated by the Chikungunya Virus nsP2 Protease.

Suwipa RamphanSarawut KhongwichitChonticha SaisawangDuangnapa KovanichAlbert J KettermanSukathida UbolPrasert AuewarakulSittiruk RoytrakulDuncan R SmithAtichat Kuadkitkan

Published in: Proteomics. Clinical applications (2017)

These results suggest that UBE2L3 is a cellular target of the CHIKV nsP2 protease, and this possibly mediates the pathogenesis of chikungunya fever.

Keyphrases

zika virus
aedes aegypti
dengue virus