Chitooligosaccharides Modified Reduction-Sensitive Liposomes: Enhanced Cytoplasmic Drug Delivery and Osteosarcomas-Tumor Inhibition in Animal Models.

Xuelei YinYingying ChiChuanyou GuoShuaishuai FengJinhu LiuKaoxiang SunZimei Wu

Published in: Pharmaceutical research (2017)

Reduction-responsive Chol-SS-COS liposomes may be an excellent platform for cytoplasmic delivery of anticancer drugs. Conjugation of liposomes with COS enhanced tumor cell uptake, antitumor effect and survival rate in animal models.

Keyphrases

drug delivery
cancer therapy
drug release
single cell
cell therapy
stem cells
bone marrow