Tocilizumab decreases T cells but not macrophages in the synovium of patients with rheumatoid arthritis while it increases the levels of serum interleukin-6 and RANKL.
Katerina ChatzidionysiouAlexandra CirciumaruBence RethiVijay JoshuaMarianne EngstromAase HensvoldErik Af KlintAnca CatrinaPublished in: RMD open (2021)
TCZ reduced synovial T-cell counts but not macrophages. A significant increase of serum IL-6 was observed in responders.