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Comparative anatomy of dissected optic lobes, optic ventricles, midbrain tectum, collicular ventricles, and aqueduct: evolutionary modifications as potential explanation for non-tumoral aqueductal anomalies in humans.

E Leon KierVivek B KalraGerald J ConlogueChristopher G FilippiSanjay Saluja
Published in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2021)
The mammalian tectum undergoes an evolutionary cephalization process consisting of relative size changes of the midbrain tectum structures. This is associated with enlargement of the occipital lobe, as part of overall neocortical expansion. Potentially, aqueductal anomalies could be explained by evolutionary modifications.
Keyphrases
  • genome wide
  • optical coherence tomography
  • optic nerve
  • dna methylation
  • gene expression
  • mass spectrometry