Naturalistic assessment of reaction time variability in older adults at risk for Alzheimer's disease.

Matthew S WelhafHannah WilksAndrew J AschenbrennerDavid A BalotaSuzanne E SchindlerTammie L S BenzingerBrian A GordonCarlos CruchagaChengjie XiongJohn C MorrisJason Hassenstab

Published in: Journal of the International Neuropsychological Society : JINS (2024)

Attentional fluctuations over 20-40 seconds assessed in daily life, are sensitive to clinical status and genetic risk for AD. RT variability appears to be an important predictor of cognitive deficits during the preclinical disease stage.

Keyphrases

physical activity
working memory
stem cells
cognitive decline
gene expression
dna methylation
mesenchymal stem cells
electron transfer