Comparison of CSF and serum neurofilament light and heavy chain as differential diagnostic biomarkers for ALS.
Steffen HalbgebauerPetra SteinackerFederico VerdeJochen WeishauptPatrick OecklChristine von ArnimJohannes DorstEmily FenebergBenjamin MayerAngela RosenbohmVincenzo SilaniAlbert C LudolphMarkus OttoPublished in: Journal of neurology, neurosurgery, and psychiatry (2021)
Our results demonstrate that CSF NfL and NfH as well as serum NfL are equally suited for the differential diagnosis of ALS, whereas serum NfH appears to be slightly less potent.