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Evaluation of an innovative new method for quantitation of plasma cells on CD138 immunohistochemistry.

Ethan GantanaNomusa MashigoIbtisam AbdullahErnest MusekwaRobert LohlunErica-Mari NellCarissa ChettyMonalisa NtobongwanaZivanai Cuthbert Chapanduka
Published in: Journal of clinical pathology (2021)
The new method is comparable to the frequently used overview estimation method in terms of intraobserver and interobserver concordance, and cost. The new method has superior interobserver concordance at low plasma cell densities. The new method appears more amenable to digital scanning and analysis.
Keyphrases
  • ms ms
  • induced apoptosis
  • stem cells
  • mass spectrometry
  • cell proliferation
  • oxidative stress
  • cell therapy
  • bone marrow
  • simultaneous determination
  • high performance liquid chromatography