Toxic, cytotoxic and genotoxic effect of plumbagin in the developmental stages of Biomphalaria glabrata (Say, 1818-intermediate host) and cercaricidal activity against the infectious agent of schistosomiasis mansoni.
Wilza Wanessa Melo FrançaAdriana Maria da SilvaEmily Gabriele Marques DinizHianna Arely Milca Fagundes SilvaDewson Rocha PereiraAna Maria Mendonça Albuquerque De MeloLuana Cassandra Breitenbach Barroso CoelhoMônica Camelo Pessoa de Azevedo AlbuquerqueHallysson Douglas Andrade de AraújoAndré de Lima AiresPublished in: Pest management science (2022)
Plumbagin proved to be a promising substance for the control of B. glabrata population, intermediate host of S. mansoni, as well as the cercariae, infective stage for humans (definitive host), while being moderately toxic to A. salina, a crustacean widely used in ecotoxicity tests. © 2022 Society of Chemical Industry.