Changes in mediators of pro-cell growth, senescence, and inflammation during murine gestation.

Narmada LavuSamantha Sheller-MillerTalar KechichianSamir CayenneElizabeth A BonneyRamkumar Menon

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2020)

Mouse fetal membranes showed a progressive senescence marker increase coincided with downregulation of cell growth factors. Development of senescence is associated with inflammation. Senescence-associated changes are natural and physiologic and indicative of fetal membranes' readiness for parturition.

Keyphrases

dna damage
endothelial cells
oxidative stress
stress induced
multiple sclerosis
single cell
signaling pathway
cell proliferation
stem cells
gestational age