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α -Chaconine Facilitates Chondrocyte Pyroptosis and Nerve Ingrowth to Aggravate Osteoarthritis Progression by Activating NF-κB Signaling.

Zhiguo ZhangFangda FuYishan BianHuihao ZhangSai YaoChengcong ZhouYuying GeHuan LuoYuying ChenWeifeng JiKun TianMing YueWeibin DuHongting JinPeijian TongChengliang WuHongfeng Ruan
Published in: Journal of inflammation research (2022)
-Chaconine intake can boost chondrocyte pyroptosis and nerve ingrowth to potentiate OA progression by activating NF-κB signaling.
Keyphrases
  • signaling pathway
  • pi k akt
  • lps induced
  • nlrp inflammasome
  • knee osteoarthritis
  • nuclear factor
  • peripheral nerve
  • oxidative stress
  • rheumatoid arthritis
  • weight gain
  • inflammatory response
  • immune response
  • weight loss