Gestational exposure to benzodiazepines or z-hypnotics and neurodevelopmental disorders in offspring: Systematic review and meta-analysis.
Chittaranjan AndradeNatarajan VaradharajanSharmi BascaraneVikas MenonPublished in: Acta psychiatrica Scandinavica (2024)
Gestational exposure to benzodiazepines or z-hypnotics was not associated with an increased risk of ASD and with only a marginally increased risk of ADHD in offspring. Given the likelihood of confounding by indication and by unmeasured variables in the original studies, our findings should reassure women who need these medications for severe anxiety or insomnia during pregnancy.
Keyphrases
- weight gain
- pregnancy outcomes
- attention deficit hyperactivity disorder
- autism spectrum disorder
- high fat diet
- pregnant women
- sleep quality
- birth weight
- body mass index
- polycystic ovary syndrome
- working memory
- intellectual disability
- early onset
- insulin resistance
- case control
- adipose tissue
- breast cancer risk
- depressive symptoms
- weight loss
- cervical cancer screening
- drug induced
- congenital heart disease
- preterm birth