Concomitant excitation and tension development are required for myocellular gene expression and protein synthesis in rat skeletal muscle.
Emil RindomJon HerskindBert BlaauwKristian OvergaardKristian VissingFrank Vincenzo de PaoliPublished in: Acta physiologica (Oxford, England) (2020)
The current study suggests that exercise-induced increases in protein synthesis as well as transcriptional signalling is dependent on the concomitant effect of excitation and tension development, whereas signalling for translation initiation is only dependent of tension development per se.