The Tumor Suppressor Interferon Regulatory Factor 2 Binding Protein 2 Regulates Hippo Pathway in Liver Cancer by a Feedback Loop in Mice.

Xue FengTiantian LuJinhui LiRuizeng YangLiqiao HuYi YeFeifei MaoLingli HeJinjin XuZuoyun WangYingbin LiuYonglong ZhangHongbin JiYun ZhaoShu-Qun ChengWei TianLei Zhang

Published in: Hepatology (Baltimore, Md.) (2020)

These results revealed the important role of IRF2BP2 in repressing liver cancer progression and highlighted a feedback loop underlying the Hippo pathway in organ-size control and tumorigenesis.

Keyphrases

binding protein
transcription factor
dendritic cells
high fat diet induced
insulin resistance