Cell behaviors and dynamics during angiogenesis.
Charles BetzAnna LenardHeinz-Georg BeltingMarkus AffolterPublished in: Development (Cambridge, England) (2017)
Vascular networks are formed and maintained through a multitude of angiogenic processes, such as sprouting, anastomosis and pruning. Only recently has it become possible to study the behavior of the endothelial cells that contribute to these networks at a single-cell level in vivo This Review summarizes what is known about endothelial cell behavior during developmental angiogenesis, focusing on the morphogenetic changes that these cells undergo.