The Association of Metabolic Syndrome and Obesity With Clinical Hip Osteoarthritis in the Study of Osteoporotic Fractures and the Osteoporotic Fractures in Men Study Cohorts.
Karen Y ChengElsa S StrotmeyerDeborah M KadoJohn T SchousboeSimon SchenkMichael NevittNancy E LaneJan M Hughes-AustinPublished in: ACR open rheumatology (2023)
In women, but not in men, MetS was associated with hip OA. In men, but not in women, obesity was associated with hip OA. These findings suggest that mechanical effects of obesity may predominate in the pathogenesis of hip OA in men, whereas metabolic effects predominate in women.
Keyphrases
- metabolic syndrome
- insulin resistance
- polycystic ovary syndrome
- weight loss
- total hip arthroplasty
- type diabetes
- knee osteoarthritis
- middle aged
- high fat diet induced
- weight gain
- adipose tissue
- uric acid
- bone mineral density
- rheumatoid arthritis
- cervical cancer screening
- breast cancer risk
- body mass index
- pregnant women