Login / Signup

A new 8,3'-neolignan from Solanum procumbens Lour.

Nhan Trung NguyenThuy Thanh Thi TranPhu Hoang DangTho Huu LeHai Xuan NguyenTruong Nhat Van DoMai Thanh Thi Nguyen
Published in: Natural product research (2021)
The phytochemical investigation of the EtOAc-soluble fraction of the aerial parts of Solanum procumbens Lour. has been carried out to obtain seven compounds, including a new 8,3'-neolignan named solacanin A (1). Their chemical structures were elucidated based on the spectroscopic data interpretation. All isolated compounds were tested for their α-glucosidase inhibitory activity. Compounds 1 and 3-6 showed inhibitory activity with IC50 values of 221.5, 18.9, 6.0, 104.1, and 219.7 µM, respectively.
Keyphrases
  • molecular docking
  • electronic health record
  • high resolution
  • big data
  • deep learning