Right heart failure due to benign metastasizing leiomyoma: a case report of this exceedingly rare condition and review of the literature.
Cesar PedrosaHeberth Cesar MiottoLeonardo Ferber DrumondMariana Magalhães AndradePaula Chaves ZilleGisele Tubertini PalharesLucas Faria Abrahao-MachadoPublished in: European heart journal. Case reports (2020)
Benign metastasizing leiomyoma to the heart is a rare condition. The pathogenesis remains controversial and includes: (i) vascular or lymphatic spread of myomatous tissue cells when leiomyoma resection or hysterectomy is performed and (ii) smooth muscle cell proliferation in multiple regions. The more usual locations of BML in the heart seem to be the tricuspid valve and the right face of the interventricular septum.
Keyphrases
- smooth muscle
- heart failure
- aortic valve
- cell proliferation
- mitral valve
- induced apoptosis
- cardiac resynchronization therapy
- aortic stenosis
- atrial fibrillation
- cell cycle arrest
- left ventricular
- lymph node
- transcatheter aortic valve replacement
- acute heart failure
- signaling pathway
- cell death
- endoplasmic reticulum stress
- coronary artery disease
- oxidative stress
- ejection fraction