A rationally designed nuclei-targeting FAPI 04-based molecular probe with enhanced tumor uptake for PET/CT and fluorescence imaging.
Xingyang ZhaoGuojin ZhangJiali ChenZirong LiYusheng ShiGuiting LiChuangyan ZhaiLiming NiePublished in: European journal of nuclear medicine and molecular imaging (2024)
F]F-FDG. This study highlights the significance of fluorescence imaging as an adjunct technique to PET/CT. Furthermore, the encouraging results obtained from the imaging of human HCC tissues hold promise for the potential application of NOTA-FAPI-MB in intraoperative fluorescent surgery guidance within clinical settings.
Keyphrases
- pet ct
- fluorescence imaging
- photodynamic therapy
- positron emission tomography
- quantum dots
- endothelial cells
- living cells
- minimally invasive
- coronary artery bypass
- gene expression
- high resolution
- patients undergoing
- cancer therapy
- induced pluripotent stem cells
- single molecule
- computed tomography
- acute coronary syndrome
- coronary artery disease
- human health
- deep learning
- artificial intelligence
- percutaneous coronary intervention