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Optimization of a solid phase extraction coupled with high performance liquid chromatography and diode array ultraviolet detection method for monitoring of different antibiotic classes residues in water samples.

Rania A MahmoudGhada M HadadRanda A Abdel SalamHatem I Mokhtar
Published in: Journal of AOAC International (2023)
HPLC-DAD and Fast HPLC methods were developed for separation of nine different antibiotics. combination with SPE procedure achieved low detection limits; from 0.2 to 3.8 ng/mL for SPE-HPLC-DAD and from 0.65 to 12.2 ng/mL for SPE-Fast HPLC.
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