Interactive Effects of a Combination of the HDAC3 and HDAC9 Genes with Diabetes Mellitus on the Risk of Ischemic Stroke.

Hung-Yi ChiouChyi Huey BaiLi-Ming LienChaur-Jong HuJiann-Shing JengSung-Chun TangHuey-Juan LinYi-Chen Hsieh

Published in: Thrombosis and haemostasis (2020)

Our results suggested that the combination of the HDAC3 and HDAC9 genes with a history of diabetes mellitus could exacerbate the deterioration of atherosclerosis, thereby increasing the risk of IS. Further studies are warranted to explore our results in other populations.

Keyphrases

histone deacetylase
genome wide
cardiovascular disease
bioinformatics analysis
glycemic control
type diabetes
adipose tissue
insulin resistance
weight loss