Spatial architecture of high-grade glioma reveals tumor heterogeneity within distinct domains.
Joel J D MoffetOluwaseun E FatunlaLutz FreytagJurgen KrielJordan J JonesSamuel J Roberts-ThomsonAnna PavenkoDavid K ScovilleLiang ZhangYan LiangAndrew P MorokoffJames R WhittleSaskia FreytagSarah A BestPublished in: Neuro-oncology advances (2023)
This primary study reveals high levels of intratumoral heterogeneity in HGGs, associated with a diverse immune landscape within spatially localized regions.
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