Micro-structural bone changes in early rheumatoid arthritis persist over 1-year despite use of disease modifying anti-rheumatic drug therapy.
Lynne M FeehanLinda L LiHeather A McKayPublished in: BMC musculoskeletal disorders (2017)
Early changes in peri-articular bone density and microstructure seen in RA are consistent with changes more commonly seen in aging bone and are slow or resistant to recover despite well controlled inflammatory joint symptoms with early DMARD therapy.
Keyphrases
- rheumatoid arthritis
- bone mineral density
- soft tissue
- disease activity
- bone regeneration
- bone loss
- oxidative stress
- ankylosing spondylitis
- emergency department
- interstitial lung disease
- physical activity
- depressive symptoms
- systemic lupus erythematosus
- idiopathic pulmonary fibrosis
- drug induced
- replacement therapy