Acetaminophen pharmacokinetics in severely obese adolescents and young adults.

Mohammed Hakim Brian Joseph AndersonHina WaliaDmitry TuminMarc P MichalskyAhsan SyedJoseph D Tobias

Published in: Paediatric anaesthesia (2018)

Current recommendations of acetaminophen to a maximum dose of 1000 mg resulted in serum concentrations below detection limits in all patients within 2 hours after administration. Dose is better predicted using total body mass with allometric scaling.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
type diabetes
liver injury
metabolic syndrome
prognostic factors
weight loss
peritoneal dialysis
clinical practice
patient reported outcomes
bariatric surgery
drug induced