Coronary artery disease-associated genetic variants and biomarkers of inflammation.
Morten Krogh ChristiansenSanne Bøjet LarsenMette NyegaardSøs Neergaard-PetersenRamzi AjjanMorten WürtzErik Lerkevang GroveAnne-Mette HvasHenrik Kjærulf JensenSteen Dalby KristensenPublished in: PloS one (2017)
In stable CAD patients, the risk allele of a common CAD-associated marker at the TOMM40/APOE locus was associated with lower hsCRP levels. No other genetic variants or the combined effect of all variants were associated with the five inflammatory biomarkers.
Keyphrases
- coronary artery disease
- end stage renal disease
- oxidative stress
- ejection fraction
- percutaneous coronary intervention
- newly diagnosed
- chronic kidney disease
- cardiovascular events
- high fat diet
- peritoneal dialysis
- gene expression
- metabolic syndrome
- adipose tissue
- copy number
- heart failure
- type diabetes
- insulin resistance
- dna methylation
- atrial fibrillation
- aortic valve
- genome wide association study
- patient reported
- mild cognitive impairment