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Ectopically Localized Epithelial Cell Clumps in Ulcers Are Derived from Reserved Crypt Stem Cells in a Mouse Model of Ulcerative Colitis.

Mio KobayashiRisako YamashitaRyo IchikawaMakoto ShibutaniToshinori Yoshida
Published in: Digestive diseases and sciences (2022)
The present results suggest that most epithelial clumps comprised crypt-derived, reserved stem cells, which might have potential for mucosal healing.
Keyphrases
  • stem cells
  • ulcerative colitis
  • mouse model
  • cell therapy
  • human health
  • risk assessment